Managing wastes from the Canadian mining and metallurgical industry is a multidisciplinary socioeconomic and environmental task. On the one hand, many industrial wastes contain metals and materials, which are considered to be strategic and critical for transformation to green technologies and the techno-economic development of society. On the other hand, industrial wastes may contain toxic and harmful components to the ecosystem. In addition, the diversity of these wastes in terms of physicochemical properties creates a need for different valorization routes; which is, indeed, a scientific and technological challenge. In this work, we present a systematic and knowledge-based approach to generate a smart database for the wastes from the mining and metallurgical industry with respect to circular economy policy, strategic mineral plan, and waste management regulations of Canada. The generated database and knowledge will form the groundwork for the development of potential metallurgical routes for the valorization of industrial wastes into in-demand products and recuperation of valuable metals and materials in a responsible and sustainable manner.